Aspirin Protect Cardio 100mg x 40
ASPIRIN PROTECT CARDIO 100MG X 40 GASTRO RESISTANT TABLETS
BAYER ASPIRIN PROTECT 100
100 mg Aspirin (acetylsalicylic acid) per tablet.
A 8 Medicines acting on the blood and haemopoietic system.
BAYER® ASPIRIN CARDIO 100 inhibits platelet aggregation by inactivation of platelet cyclooxygenase, the enzyme that produces the cyclic endoperoxide precursor of thromboxane A2.
Indications related to inhibition of platelet aggregation: To reduce the risk of myocardial infarction in patients with unstable angina or in patients who have had a previous myocardial infarction. To reduce the risk of recurrent transient ischaemic attacks or stroke in men who have had transient ischaemia of the brain due to fibrin platelet emboli. To reduce the risk of graft occlusion following aortocoronary by-pass surgery.
Patients with peptic or duodenal ulcers, haemophilia, thrombocytopenia or other bleeding tendencies, or intolerance (hypersensitivity) to aspirin or other salicylates, severe renal impairment and patients receiving oral anticoagulant therapy. Aspirin should not be taken during pregnancy and lactation, except under the advice and supervision of a medical doctor.
The optimal dose for inhibition of platelet aggregation in humans is not known. Do not use BAYER ASPIRIN CARDIO 100 for indications related to the inhibition of platelet aggregation unless directed by a doctor. Aspirin has been implicated in Reye’s Syndrome, a rare but serious illness in children and teenagers with chickenpox and influenza. A doctor should be consulted before use in such patients.
DOSAGE AND DIRECTIONS FOR USE
Adults: 100 to 300 mg to be taken every day, preferably at the same time each day.
The tablets should be swallowed whole. Do not chew, break or crush the tablets as this will destroy the protective effect of the enteric coating.
SIDE EFFECTS AND SPECIAL PRECAUTIONS
- Concomitant therapy with other gastric irritants, such as non-steroidal anti-inflammatory agents may increase the risk of gastric irritation.
- Aspirin may increase the risk of gastrointestinal bleeding when taken simultaneously with corticosteroids or alcohol.
- BAYER ASPIRIN CARDIO 100 should be used with caution in patients who are hypersensitive to other anti-inflammatory agents or allergens.
- BAYER ASPIRIN CARDIO 100 should be withdrawn one week before surgery because of the possibility of increasing the bleeding times.
- Dizziness, irritation of the gastric mucosa and resultant dyspepsia, erosion, ulceration, haematemesis, and melaena may occur.
- Some persons, especially asthmatics, exhibit notable sensitivity to aspirin which may provoke various hypersensitivity reactions which may include skin eruptions, urticaria, angioedema, paroxysmal bronchospasm and dyspnoea.
- It should be administered with caution to patients with impaired renal function, in the presence of severe liver disease, in patients with a history of gastrointestinal disorders such as peptic ulcers, ulcerative colitis and Crohn’s disease, dyspepsia, anaemia and when the patient is dehydrated.
- Aspirin may enhance the activity of coumarin anticoagulants, methotrexate, oral anti-diabetic preparations, valproic acid and sulphonamides.
- Aspirin diminishes the effects of anti-gout preparations such as probenecid and sulphinpyrazone. Barbiturates and other sedatives may mask the respiratory symptoms of aspirin overdosage and have been reported to enhance its toxicity.
- Prolonged use of high doses may lead to anaemia, blood dyscrasia, gastro-intestinal haemorrhage and peptic ulceration.
Interference with laboratory tests:
- Salicylates may produce falsely increased results for blood creatinine, urate (low dose aspirin) and urea. Falsely decreased results may be obtained for blood thyroxine and urate (>4g/day aspirin) and for urinary 5-HIAA (with nitrosonaphthol method). Urinary VMA (HMMA) levels may be falsely increased or decreased depending on the method of analysis.
- Urinary glucose oxidase: Aspirin may cause a false-negative test in the presence of glycosuria.
KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT
These include dizziness, tinnitus, sweating, nausea, vomiting, altered glucose metabolism, mental confusion, hyperventilation, respiratory alkalosis, metabolic acidosis, ketosis, fluid and electrolyte losses.
Depression of the central nervous system may lead to coma, cardiovascular collapse and respiratory failure.
In children, serious signs of overdosage may develop rapidly.
In cases of overdosage, consult a doctor immediately.
Gastric lavage forced alkaline diuresis, restoration of fluid, electrolyte and acid balance, dialysis and supportive therapy may be required.
White, round, coated tablets.
100 mg tablets blister packed into packs of 40.
Store below 25°C. Keep out of reach of children.