Sinquanon Kids 7 Sachets

Sinquanon Kids 7 Sachets

WHAT IS GOOD TO KNOW ABOUT THE EFFECT OF ANTIBIOTIC TREATMENT ON THE GASTROINTESTINAL MICROFLORA?

What is a microbiome?

The aggregate of microorganisms normally inhabiting the human body is known as microflora, microbiota or microbiome. The human microbiome has been found to consist of approximately 100 trillion bacterial cells – 10 times more than the number of cells in the human body.

Microorganisms colonise or inhabit every surface of the human body, which has access to the environment, including the skin, the respiratory, urogenital and gastrointestinal tracts.

The colon is the most colonised part of the gastrointestinal tract, being inhabited by 1 trillion microorganisms per gram of faecal content, represented by hundreds of species.

In most general terms, microorganisms can be distinguished as useful and harmful to humans.

What are the functions of the microbiome in the human body?

Useful bacteria perform important metabolic, protective and immunological functions for human health, manifested as:

Improved digestion and absorption of nutrients that the human organism cannot absorb, which are accumulated in the ascending part of the colon as a result of the slow speed of the intestinal passage;

Synthesis of vitamins;

Inhibited growth of pathogenic (harmful) bacteria;

Stimulation of the immune system.

The normal microflora is a stable ecosystem. Differences in the composition of the microflora exist between individuals in terms of species and microbial number, but the microflora remains a relatively constant value during the entire lifetime of an individual. Certain factors can contribute to destroying the balance in that ecosystem, the administration of antibiotics being a leading cause of that process.

What is happening during the antibiotic treatment?

The role of antibiotics for treatment of bacterial infections is indispensable, but while coping with the pathogenic bacteria, they inflict fatal damage to the microflora, which can have either short-term or long-term clinical manifestations.

The complete recovery of the microbiome after antibiotic therapy takes a long time: between several months and several years. In some cases, individual strains (subtypes of a certain microorganism) are completely destroyed and the microbiome cannot recover to its initial levels. This triggers disorders in the regulation of many processes in the organism and is a prerequisite for the manifestation of diseases – both connected to the gastrointestinal tract and outside it.

One of the most frequent complications immediately after antibiotic therapy is antibiotic-associated diarrhoea that can affect more than 30% of the patients. The irritable bowel syndrome is another complication that can occur either immediately after the antibiotic course, or months and even years after it.

An increasing volume of research evidence supports the interrelation between the disturbed gastrointestinal microflora and morbid states outside the gastrointestinal tract, which may find clinical manifestation years after the intake of antibiotics. Altered ratio of “good” and “bad” bacteria is observed in diseases like asthma, autism and in the case of various allergic reactions. The disturbed ratio of “good” and “bad” bacteria also results in maintaining a permanent inflammatory reaction, which is one of the leading factors for the emergence and development of metabolic syndrome and diabetes mellitus.

Some diseases of the cardiovascular and bone systems can be explained with reduced synthesis of vitamin K, which is produced only by microorganisms in the gastrointestinal tract.

WHAT IS SINQUANON KIDS?

SINQUANON KIDS is a probiotic that has been specially designed to maintain normal gastrointestinal flora during and after antibiotic treatment for 0-5 years old children.

It is a blend of 13 specially selected probiotic strains in a dose of 15 billion CFU*.

Content of one daily dose – 1 sachet (15 billion live microorganisms):

Ingredients in the recommended daily dose:

Bifidobacterium Spp.                                                      6 billion CFU*

Bifidobacterium longum ssp longum BL21 

Bifidobacterium breve BВr60 

Bifidobacterium bifidum BBi32 

Bifidobacterium longum ssp infantis BI45

Bifidobacterium lactis BLa80

Lactobacillus Spp.                                                          4 billion CFU*

Lactobacillus acidophilus LA85

Lactobacillus reuteri LR08

Lactobacillus plantarum LP90

Lactobacillus casei LC89

Lactobacillus paracasei LC86

Lactobacillus gasseri LG08

Lactobacillus rhamnosus GG

Saccharomyces boulardii                                             5 billion CFU*

Other ingredients: maltodextrin and flavor raspberry, sweetener -  stevia with erythritol

*CFU – colony-forming units (number of live cells)

SINQUANON KIDS is a food additive.

SINQUANON KIDS is gluten and lactose free.

HOW DOES SINQUANON KIDS WORK AND WHO IS IT INTENDED FOR?

SINQUANON KIDS is a special selection of 13 probiotic strains: Lactobacillus, Bifidobacterium and Saccharomyces with a high natural resistance to antibiotics, in a dose of 15 billion live cells, which maintains normal intestinal microflora during and after antibiotic therapy.

Lactobacilli and Bifidobacteria are lactic acid bacteria, which are the most numerous typical inhabitants of the human gastrointestinal tract. They produce substances and metabolites that are important for the organism and for the existence of the intestinal flora.

Antibiotic treatment causes a strong reduction of the number of Lactobacilli and Bifidobacteria.

SINQUANON KIDS contains a high dose (10 billion) of live Lactobacilli and Bifidobacteria, which results in rapid attaining of high concentrations of useful microorganisms in the intestines.

SINQUANON KIDS also contains Saccharomyces boulardii – probiotic yeast that is not affected by antibiotics. It produces enzymes that disintegrate the toxins in the intestines and contributes to maintaining a normal intestinal microflora.

The content of different strains in SINQUANON KIDS favours the mutual potentiating of their beneficial effects.

The strains in SINQUANON KIDS divide fast and double their mass approximately at 20-minute intervals. Owing to this, they manage to maintain the intestinal microflora closer to its physiological levels during antibiotic treatment.

The strains in SINQUANON KIDS are specially selected with an increased natural resistance against the most frequently used antibiotics, which guarantees their survival and effectiveness.

SINQUANON KIDS also contains a prebiotic blend, specially designed for the needs of the 13 probiotic strains included in its composition. It includes three types of oligosaccharides that are not degradable by the human organism, which serve as food both for the probiotic strains and for the useful bacteria living normally in the gastrointestinal tract. The prebiotics assist the strains in SINQUANON KIDS to start dividing rapidly.

WHO SHOULD NOT TAKE SINQUANON KIDS?

Do not take SINQUANON KIDS if you have ever had an allergic reaction to any of the ingredients of the product.

SINQUANON KIDS is lactose and gluten free.

WHAT ARE THE SIDE EFFECTS OF SINQUANON KIDS?

No side effects and contraindications of the administration of the product are known so far. Its tolerance is very good, which allows for safe use for prolonged periods of time. 

HOW SHOULD SINQUANON KIDS BE ADMINISTERED?

Children aged 0-5 years should take 1 sachet daily from the first day of the antibiotic therapy.

After completion of the antibiotic therapy, it is important for the administration of SINQUANON KIDS to continue for at least two more weeks in the same dose for attaining a longer-lasting and reliable effect. The recommended interval between the intake of the antibiotic and SINQUANON KIDS is at least 2 hours.

Do not take SINQUANON KIDS with hot or alcoholic beverages so as not to destroy the living bacteria in the sachet.

STORAGE

SINQUANON KIDS is to be kept in its original package at a temperature not exceeding 25°С, in a dry place without exposure to direct sunlight, which is inaccessible to children.

Do not use the product after its expiry date or if its packaging is not intact.